Gold Vs. Ozempic in Weight Loss Effectiveness - Jaaj.Club
Poll
Writing books knowing that they can influence someone's destiny is...


Events

07.09.2025 17:28
***

Started
from the publishing house Collection Jaaj.Club.

Write a science fiction story up to 1 author page and get a chance to be included in a collective collection and get reviewed by renowned authors.

Jury of the contest

Alexander Svistunov
Fantasy writer, member of the Union of Writers of Uzbekistan and the Council for Adventure and Fantastic Literature of the Union of Writers of Russia.

Katerina Popova
A modern writer working in the genre of mysticism, fantasy and adventure thriller. The author does not deprive her works of lightness, humor and self-irony.

Maria Kucherova
Poet and prose writer from Tashkent. The author works in the genres of mysticism, drama and thriller, creates a series of novels and novellas in a single fictional universe.

Konstantin Normaer
A writer working at the intersection of genres: from fantasy detective and steampunk to dark fantasy and mystical realism.

Yana Gros
Writer-prose writer, the main direction - grotesque, social satire, reaction to the processes that are happening today. Laureate and diploma winner of international competitions.

Jerome
Author of the "Lost Worlds" series, specializing in space fiction and time travel. Author of numerous science fiction stories.

Artyom Gorokhov
Artem Gorokhov
Writer-prose writer, author of novels and many works of small prose. The head of seminars of creative community of poets and prose writers.

Olga Sergeyeva
Author of the collection of fantastic stories "Signal". Master of science fiction and mysticism, exploring time, memory and the limits of human possibilities.

***
12.08.2025 18:44
***

On Sale!

Echo of Destruction is a new post-apocalyptic novel
Zoya Biryukova.

A post-catastrophe world, an ancient war between vampires and werewolves, and a ritual that will decide the fate of humanity.


Zoya Biryukova is a gamer and dark fantasy fan. Her love for the worlds of vampires and werewolves inspired her to create her own story about the post-apocalypse and ancient powers.

***
02.07.2025 20:55
***

Already on sale!

A new story from Katerina Popova in a mystical novel


Anybody Alive? - Katerina Popova read online

***

Comments

Очень много запятых.
12.10.2025 Гость
Спасибо большое! Очень рад, что вам понравилось.
Особенно оценил бы ваши слова главный герой рассказа - "Логику Александр Григорьевич уважал" )
12.10.2025 TatarRish
Интересное и логически построенное произведение с философской развязкой, большое спасибо!
11.10.2025 Formica
Интересно. Необычно. По-настоящему фантастично. Большое спасибо!
10.10.2025 Formica
Навуходоноссор -- ВОПЛОЩЕНИЕ АПОКАЛИПТИЧЕСКОГО ЗВЕРЯ 666 ВЫ в статье воспеваете сатанинские дела, восхищаясь и превознося мерзавца, для которого люди и народ собственный -- был МУСОР. Храм Соломона разрушил, над израильтянами -- ИЗДЕВАЛСЯ.. Поэтому стал ЗВЕРЕМ 666 ( из современных -- похож на ИВАНА 4 ГРОЗНОГО -- опричнина, паранойик,мания преследования; выл как собака -- как инкарнация его; и ещё -- как Иосиф Джугашвили __ этот тоже с наслаждением убивал людей; 50 млн собственного народа загубил, геноцид устроил))
10.10.2025 Гость

Gold Vs. Ozempic in Weight Loss Effectiveness

12.02.2025 Рубрика: Interesting
Автор: vassyap
Книга: 
4436 1 0 10 739
Scientific research is increasingly confirming that gold nanoparticles can cause targeted weight loss by acting exclusively on fat deposits.
Gold Vs. Ozempic in Weight Loss Effectiveness
фото: newatlas.com
Scientific research is increasingly confirming that gold nanoparticles can cause targeted weight loss by acting solely on fat deposits without negatively affecting muscle tissue.

In addition, these nanoparticles demonstrate a wide range of positive effects for the body - from a powerful anti-inflammatory effect to stabilize blood glucose levels, which makes them a promising area in medicine and biotechnology.

Researchers from Egypt's Alexandria University have expanded the knowledge of gold nanoparticles (AuNPs) by demonstrating that weekly doses can lead to significant weight loss - perhaps even greater than GLP-1 class drugs (such as Ozempic) - and, unlike those drugs, showed no signs of muscle wasting.

But there's a catch. Although the results look promising - a 36% reduction in fat mass over nine weeks, while GLP-1 drugs usually lead to a loss of 10-20% of body weight (of which up to 20% is muscle) - so far all studies have been limited to animal trials. Scientists have yet to confirm the efficacy and safety of this method for humans. However, this study brings the new obesity treatment one step closer to human trials.

In a study on rats, scientists compared different doses of AuNPs with a control (no treatment) and the existing weight-loss drug orlistat (trade name Xenical). During the experiment, rats with diet-induced obesity were divided into groups and subjected to different treatments for nine weeks. At the end of the study, scientists analyzed in detail their body composition, the state of internal organs and key metabolic indicators.

The results were impressive: high weekly doses of gold nanoparticles (AuNPs) led to a significant reduction in fat deposits, while promoting increased muscle mass and improved metabolism in the test animals.

In addition, as in previous studies, there was an increase in blood glucose levels, a decrease in inflammation, and an attenuation of oxidative stress.

Histologic analysis showed that AuNPs promoted tissue repair in the liver and kidney, while in contrast, the traditional weight-loss drug orlistat had a negative effect on these organs.

Using bioelectrical bioimpedance analysis (BIA), a common non-invasive method for measuring body fat mass (BFM), body fat free mass (BFFF) and total body water (TBW), the researchers found that AuNPs are also able to target the right lipid cells.

The high weekly dose group experienced an average fat loss of 36%, which was more effective than daily high doses (33%) and significantly better than the rats taking orlistat (18%). In fact, twice as effective.

"BIA and body composition diagnostics showed that high doses of gold nanoparticles resulted in significant reductions in fat mass and improvements in skeletal and muscular structure parameters, making them a promising alternative to current obesity control methods," the researchers said in the paper.

"Previous studies have shown that orlistat can curb weight gain associated with obesity. However, AuNPs show a more pronounced effect due to their anti-inflammatory and antioxidant properties, as well as their unique ability to selectively accumulate in adipose tissue, which enhances their effects on fat deposits," the scientists add.

In an era where GLP-1 drugs dominate obesity treatment, it is easy to overlook the existence of alternative remedies such as orlistat. Unlike Semaglutide (known by the trade name Wegovy) and Ozempic, orlistat works differently - it inhibits the absorption of fats in the intestine.

Although its long-term efficacy is inferior to GLP-1 (average weight loss is about 6%), this drug remains more affordable and may be an alternative for those who experience severe side effects from GLP-1.

00aahiomj1.jpg
Photo: alev.biz

To date, there have been no direct comparisons between GLP-1 and gold nanoparticles. However, given the ability of AuNPs to preserve muscle mass, they can be considered not as a replacement or competitor of GLP-1 drugs, but as an additional method of therapy that expands the possibilities of obesity treatment.

AuNPs have been in the spotlight for the past decade, and now there is growing interest in unlocking their potential for weight loss. The latest study builds on earlier results presented in these 2018 and 2023 studies.

Currently, gold nanoparticles are already used in a number of medical technologies, including cancer treatment and targeted drug delivery. However, their use in the treatment of obesity is still at the preclinical stage - no human trials have been conducted yet.

One of the key reasons for this is the lack of understanding of potential risks, in particular the possible toxicity of AuNPs in long-term use.

"Since an estimated 60% of the world's population will be overweight or obese by 2030, we urgently need innovative treatments for obesity," the researchers add. "Although AuNPs show promise for the treatment of obesity, more research is needed to address whether these particles pose a risk to human organs."

The study was published in the journal Science Reports.

Sign up for our free weekly newsletter

Every week Jaaj.Club publishes many articles, stories and poems. Reading them all is a very difficult task. Subscribing to the newsletter will solve this problem: you will receive similar materials from the site on the selected topic for the last week by email.
Enter your Email
Хотите поднять публикацию в ТОП и разместить её на главной странице?

Как поддерживать нормальный вес

Многие люди страдают из-за сильных проблем с лишним весом. Избыточные киллограммы становится огромной тяжестью. Читать далее »

Мечехвосты освобождаются от биомедицинских испытаний

В течение 40 лет исследователи полагались на кровь мечехвостов для выявления эндотоксинов в препаратах. Синтетические альтернативы и обновлённые нормативные акты могут положить конец этой практике. Читать далее »

Чернила каракатицы помогут уберечь людей от акул

Имитация чернил, выделяемых биолюминесцентными головоногими моллюсками, может стать инновационным способом защиты как акул, так и людей. Читать далее »

Найденная в Антарктиде окаменелость - самая ранняя из известных современных птиц

Недавно описанная окаменелость относит самую раннюю из известных современных птиц к древним родственникам уток и гусей. Читать далее »

Комментарии

-Комментариев нет-